Март/Апрель 2015, том 7, номер 2

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■ Лекции

Абатуров А.Е., Никулина А.А., Петренко Л.Л. Лактазная недостаточность у детей 2015;Т7(2):44-50

Лактазная недостаточность у детей

Абатуров А.Е., Никулина А.А., Петренко Л.Л.

ГУ «Днепропетровская медицинская академия» МЗ Украины, Днепропетровск, Украина

■ Резюме:

В статье представлены критерии, распространенность, особенности течения, современные методы диагностики и лечения лактазной недостаточности у детей. Показана взаимосвязь с сопутствующей патологией, учитывающая генотип полиморфизма гена лактазы. Генотип лактазы С/С-13910, ассоциированный с алактазией взрослых, чаще встречается среди детей с атопическими заболеваниями (бронхиальной астмой, поллинозом, атопическим дерматитом, аллергией к белкам коровьего молока). Носителей данного генотипа отличает более высокий уро- вень колонизации бифидобактерий под действием лактозы, чем в общей популяции и предрасположенность к развитию вторичной лактазной недостаточности. Генотип Т/Т 13910 гена LCT ассоциирован с лактазной персистенцией на протяжении всей жизни.

■ Ключевые слова:

лактоза, лактазная недостаточность, дети, полиморфизм лактазы.

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